The short answer
A retail pharmacy takes ordinary card-present payments and a second class of payment that most retailers never see: health FSA and HRA benefit cards, whose acceptance turns on federal tax guidance rather than on card network rules. IRS Notice 2007-2 states that after December 31, 2008, health FSA and HRA debit cards may not be used at stores with the Drug Stores and Pharmacies merchant category code unless the store participates in an inventory information approval system as described in Notice 2006-69, or, on a store-location-by-store-location basis, 90 percent of the store's gross receipts during the prior taxable year consisted of items qualifying as medical care expenses under section 213(d). Everything else at the counter prices as normal retail: CPS/Retail, Debit at 0.80% + $0.15 and Product 2 consumer credit at 1.51% + $0.10 for all other products on Visa's schedule effective April 18, 2026.
Your merchant category code is doing more work here than anywhere else
In most of retail the merchant category code is a classification detail with interchange consequences. In a pharmacy it is closer to a licence. Revenue Ruling 2003-43 described benefit card programmes in which the card can only be used at merchants and service providers with merchant category codes related to health care — physicians, pharmacies, dentists, vision care offices, hospitals and other medical care providers — and use of the card anywhere else would be rejected. That is why a benefit card approves at a pharmacy counter and declines at a hardware store. It is also why a mis-assigned code is a commercial problem rather than a paperwork one: a pharmacy boarded under a general retail code will decline the exact transactions it exists to accept, and the customer will assume the card is broken. When you board an account or move providers, confirm the assigned code in writing, confirm it per location if you have more than one, and test a benefit card on the live terminal before you rely on the answer. IRS Notice 2007-2 also closed the older route for everyone else: after December 31, 2007, health FSA and HRA debit cards may not be used at any store, vendor or merchant that does not have a health-care-related merchant category code unless that merchant has implemented an inventory information approval system.
The 90 percent test is measured per location and looks backwards
The part of Notice 2007-2 that pharmacy operators most often misread is the alternative to running an inventory information approval system. The notice permits a store with the Drug Stores and Pharmacies code to continue accepting these cards where, on a store-location-by-store-location basis, 90 percent of the store's gross receipts during the prior taxable year consisted of items which qualify as expenses for medical care under section 213(d), including nonprescription medications as described in Revenue Ruling 2003-102. Three features of that sentence matter operationally. It is location by location, so a chain cannot pass on a group average and a single busy front-of-store location can fail while its sister store passes. It is measured on the prior taxable year, so the test you are relying on today is a fact about last year's mix and a deliberate expansion of the gift, snack and cosmetics aisles is a decision about next year's eligibility. And it is gross receipts, not prescription count, so a high-volume dispensary with a large general merchandise floor can fail a test that a small dispensary passes easily. Track the ratio deliberately rather than discovering it. This is general information, not tax advice, current as of September 17, 2026; confirm your own position with your tax adviser.
What the register has to do when only half the basket qualifies
The mechanics of a mixed basket are set out in Notice 2006-69 and they are specific. Where a merchant participates in an inventory information approval system, inventory information is matched at the point of sale. If all items purchased are section 213(d) medical expenses, the entire transaction is approved, subject to the coverage limitations of the health FSA or HRA. If only some of the items qualify, the transaction is approved only as to the qualifying items, and the merchant or service provider requests additional payment from the employee for the items that do not meet the definition of medical care under section 213(d). The merchant also requests additional payment where the employee does not have sufficient coverage remaining to buy the qualifying items. In plain terms: the benefit card is expected to part-pay the basket and the register is expected to collect the remainder on another tender, in one continuous sale, without the cashier making any judgement about what qualifies. That is a POS capability question. Ask your provider, in writing, whether the system supports split tender against a partial approval on these cards, whether the eligibility file is maintained for you, and who updates it when the eligible-item list changes.
The ordinary card side of a pharmacy counter
Strip out the benefit cards and a pharmacy is a card-present retailer with a low-to-middling ticket, a high transaction count and a meaningful debit share. The programs below, effective April 18, 2026, are the ones the rest of the counter reaches. Two notes. First, the Healthcare programs in Visa's consumer credit schedule carry an explicit floor: Healthcare 2 card present and Healthcare 1 card not present both apply to transactions of $500 or more, which is above almost every retail pharmacy transaction, so a retail counter will rarely see those rows even though the word looks like an obvious fit. Second, the per-item cents dominate at this ticket size — a $0.15 fixed component on a $19 co-payment is worth 0.79% on its own.
| Program | Applies to | Rate |
|---|---|---|
| CPS/Retail, Debit | Exempt debit, chip or contactless | 0.80% + $0.15 |
| CPS/Retail, Debit | Regulated debit | 0.05% + $0.21, plus $0.01 for certified issuers |
| CPS/Small Ticket, Debit | Exempt debit, small basket, PIN on Visa Network 002 | 1.55% + $0.04 |
| CPS/Retail, Prepaid | Exempt prepaid | 1.15% + $0.15 |
| Product 2, All Other Products | Consumer credit | 1.51% + $0.10 |
| Healthcare 2, All Other Products | Consumer credit, card present, $500 or more | 1.43% + $0.05 |
| Healthcare 1, All Other Products | Consumer credit, card not present, $500 or more | 1.53% + $0.05 |
| CPS/Retail Key Entry, Debit | Exempt debit, keyed | 1.65% + $0.15 |
| Non-Qualified Consumer Credit | Consumer credit, failed qualification | 3.15% + $0.10 |
Copayment matching, and why your ticket amounts are not random
There is one more piece of the substantiation machinery that shows up at a pharmacy counter. Notice 2006-69 expands the copayment match method so that where an employer's health plan has copayments in specific dollar amounts, a transaction at a health care provider identified by its merchant category code that equals an exact multiple of not more than five times the copayment for the specific service — a pharmacy benefit copayment, for example — is automatically substantiated. The practical effect is that a customer filling five prescriptions at a $10 copayment can clear automatically at $50, while the same customer adding a $4 item to the same transaction cannot. That is not something you control, and it is emphatically not something a cashier should be explaining. But it is worth understanding, because it is the reason a customer sometimes asks to ring prescriptions separately from everything else, and the reason that request is entirely reasonable rather than a sign of anything wrong.
Compliance, and the two things to get in writing
PCI DSS applies to every merchant that accepts payment cards; the PCI Security Standards Council publishes merchant guidance and the listings of validated PIN transaction security devices, and your self-assessment questionnaire type follows from how the pharmacy takes payment — a counter with a delivery or phone-order channel sits differently from a purely card-present one. Pharmacies also carry patient privacy obligations under separate health privacy law that no payment provider can discharge for you; keep the payment environment and the dispensing system apart unless your integrator can document exactly what crosses between them. Two things to get in writing before you sign anything: the merchant category code assigned to each location, and whether the platform supports partial approval with split tender on benefit cards. Everything else — the rate, the term, the equipment — is a normal negotiation. Those two are the ones that determine whether the register can do its job.
About the rate tables on this page: Visa is the only card network that publishes a public US merchant interchange schedule, so the rate tables on this site are Visa-only. Mastercard, American Express and Discover do not publish an equivalent US merchant schedule, and their rates are neither shown above nor implied by these figures. Ask your processor for the rates that apply to each network on your account.
Key takeaways
- After December 31, 2008 benefit cards may not be used at Drug Stores and Pharmacies MCC stores without an IIAS or the 90 percent test
- The 90 percent test is applied store location by store location, on the prior taxable year's gross receipts
- Growing the front-of-store merchandise mix is a decision about next year's eligibility
- Under an IIAS a mixed basket is approved only as to the qualifying items; the register collects the rest
- Confirm the assigned merchant category code per location in writing and test a live benefit card
- Visa's Healthcare interchange programs apply only to transactions of $500 or more
- At a $19 ticket the $0.15 fixed component is worth 0.79% on its own
- Copayment match covers exact multiples of not more than five times the copayment
Related guides
- Retail payment processing and POS
- Accepting HSA and FSA Cards: IIAS and the 90% Rule
- Retail Credit Card Processing: What a Store Pays
- Medical Practices: Collecting Patient Balances Faster
- Merchant Category Codes (MCC): What Merchants Should Know
- Small Tickets: What Visa's Schedule Charges on a $4 Sale
- PCI Compliance for Small Businesses: A Plain Guide
Sources
- Internal Revenue Service, Notice 2007-2 (checked 2026-09-17)
- Internal Revenue Service, Notice 2006-69 (checked 2026-09-17)
- Visa – Visa USA Interchange Reimbursement Fees (18 April 2026) (checked 2026-09-17)
- Visa Core Rules and Visa Product and Service Rules (18 April 2026) (checked 2026-09-17)
- PCI Security Standards Council – Merchants (checked 2026-09-17)
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